MK4MDD

Brain Morphology and Function Report

Basic Information
Name Inferior frontal gyrus
Brain Morphology "The inferior frontal gyrus is a gyrus of the frontal lobe of the human brain. Its superior border is the inferior frontal sulcus, its inferior border the lateral fissure, and its posterior border is the inferior precentral sulcus. Above it is the middle frontal gyrus, behind it the precentral gyrus."
Brain Function "The right inferior frontal gyrus has been typically implicated in go/no go tasks. In such a task, the participant has to inhibit a prepotent response (for instance stop pressing a button when a red signal appears). It seems that the same area is also implicated in risk aversion: a study found that higher risk aversion correlated with higher activity at inferior frontal gyrus. This might be explained as an inhibition signal to accept a risky option. Disruption of activity of this area with Transcranial Magnetic Stimulation or Direct Current Stimulation (tDCS) indeed leads to change in risk attitudes, as behaviorally demonstrated by choices over risky outcomes."
Picture Inferior frontal gyrus From Wiki. Magnify
No. of Studies (Positive/Negative) 6(6/0) Help

Positive relationships between Inferior frontal gyrus and MDD (count: 3)
Name in Literature Reference Research Type Statistical Result Relation Description Help
inferior frontal gyri Dichter, 2009 patients and normal controls During sad blocks, the MDD group demonstrated greater activa...... During sad blocks, the MDD group demonstrated greater activation in a number of prefrontal regions, including the mid-, inferior, and orbito-frontal gyri and the anterior cingulate, suggesting that relatively more prefrontal brain activation was required to disengage from the sad images to respond to the target events. More...
inferior frontal gyrus Matthews, 2009 patients and normal controls A group by trial difficulty interaction on error-related act...... A group by trial difficulty interaction on error-related activation in bilateral inferior frontal gyrus and left supragenual ACC was observed, suggesting a demand-specific failure of this circuitry in MDD. More...
inferior frontal gyrus Klok, 2010 patients and normal controls P-value < .05 Significantly lower expression levels (30-50%) were detected...... Significantly lower expression levels (30-50%) were detected for MR or GR in hippocampal, inferior frontal gyrus and cingulate gyrus tissue from MDD patients (p < .05) More...

Positive relationships between Inferior frontal gyrus and other components at different levels (count: 3) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of Inferior frontal gyrus in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Inferior frontal gyrus and MDD (count: 0)
Negative relationships between Inferior frontal gyrus and other components at different levels (count: 0) Help