MK4MDD

Molecule Report

Basic Information
Name Glucocorticoids
Description A group of CORTICOSTEROIDS that affect carbohydrate metabolism ( GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
MeSH ID D005938
No. of Studies (Positive/Negative) 1(1/0) Help

Positive relationship between Glucocorticoids and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
glucocorticoids Gaiteri, 2010 patients and normal controls P-value<0.01 Biological networks and signal transduction pathways corresp...... Biological networks and signal transduction pathways corresponding to the identified gene set suggested putative dysregulated functions for several hormone-type factors previously implicated in depression (insulin, interleukin-1, thyroid hormone, estradiol and glucocorticoids; p<0.01 for association with depression-related networks). More...

Positive relationships between Glucocorticoids and other components at different levels (count: 0) Help
Positive relationship network of Glucocorticoids in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationship between Glucocorticoids and MDD (count: 0)
Negative relationships between Glucocorticoids and other components at different levels (count: 0) Help