MK4MDD

Gene Report

Basic Information
Approved Symbol GOT2
Approved Name glutamic-oxaloacetic transaminase 2, mitochondrial
Previous Name "glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)"
Symbol Alias mitAAT, KATIV, KAT4
Name Alias "kynurenine aminotransferase IV", "aspartate aminotransferase 2", "aspartate transaminase 2"
Location 16q21
Position chr16:58768133-58768233 (-)
External Links Entrez Gene: 2806
Ensembl: ENSG00000125166
UCSC: uc002eof.1
HGNC ID: 4433
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between GOT2 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
GOT2 Jansen R, 2015 patients and normal controls P-value=0.000263;FDR=0.0975;beta=-0.242 we found 129 genes (142 probesets) differentially expressed ...... we found 129 genes (142 probesets) differentially expressed between the control and current MDD groups (FDR<0.1) More...

Positive relationships between GOT2 and other components at different levels (count: 0) Help
Positive relationship network of GOT2 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between GOT2 and MDD (count: 0)
Negative relationships between GOT2 and other components at different levels (count: 0) Help
GOT2 related SNPs in MK4MDD (count: 0)
GOT2 related proteins in MK4MDD (count: 0)
GOT2 related GO terms (count: 37)
GOT2 related KEGG pathways (count: 5)
GOT2 related BioCarta pathways (count: 0)
GOT2 related Reactome pathways (count: 5)
GOT2 related interactors from protein-protein interaction data in HPRD (count: 6)