The entorhinal cortex (EC) is located in the medial temporal lobe and functions as a hub in a widespread network for memory and navigation.
"The EC is the main interface between the hippocampus and neocortex. The EC-hippocampus system plays an important role in autobiographical/declarative/episodic memories and in particular spatial memories including memory formation, memory consolidation, and memory optimization in sleep. The EC is also responsible for the pre-processing (familiarity) of the input signals in the reflex nictitating membrane response of classical trace conditioning, the association of impulses from the eye and the ear occurs in the entorhinal cortex."
No. of Studies (Positive/Negative)
Positive relationships between Entorhinal cortex and MDD (count: 2)
We found decreased VGLUT1 mRNA expression in both MDD and BD......
We found decreased VGLUT1 mRNA expression in both MDD and BD in the entorhinal cortex (ERC), decreased VGLUT2 mRNA expression in MDD in the middle temporal gyrusMore...
Remitted MDD was related to smaller entorhinal cortex volume......
Remitted MDD was related to smaller entorhinal cortex volumes (p < .05). More...
Positive relationships between Entorhinal cortex and other components at different levels (count: 0)
Positive relationship network of Entorhinal cortex in MK4MDD
Network loading ...
1. The different color of the nodes denotes the level of the nodes.
Protein and Other Molecule
Cell and Molecular Pathway
Cognition and Behavior
Symptoms and Signs
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node.
Right-click will show also the menus to link to the report page of the node and remove the node and related edges.
Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web
Negative relationships between Entorhinal cortex and MDD (count: 0)
Negative relationships between Entorhinal cortex and other components at different levels (count: 0)
Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
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Last update: October 10, 2015