MK4MDD

Gene Report

Basic Information
Approved Symbol EGR3
Approved Name early growth response 3
Symbol Alias PILOT
Name Alias "zinc finger protein pilot"
Location 8p23-p21
Position chr8:22550458-22550815 (-)
External Links Entrez Gene: 1960
Ensembl: ENSG00000179388
UCSC: uc003xcm.1
HGNC ID: 3240
No. of Studies (Positive/Negative) 2(1/1) Help
Type Literature-origin

Positive relationships between EGR3 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
EGR3 Carvalho LA, 2014 patients and normal controls FC=2.4; P-value=0.027 Thirty-four of the 47 monocyte inflammatory-related genes w...... Thirty-four of the 47 monocyte inflammatory-related genes were significantly upregulated and 2 were significantly downregulated as compared to controls More...

Positive relationships between EGR3 and other components at different levels (count: 0) Help
Positive relationship network of EGR3 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between EGR3 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description
EGR3 Byrne EM, 2014 Patients and nomal controls P-Values=0.63 These results show that while there are several circadian ge...... These results show that while there are several circadian genes that harbor SNPs with nominally significant P-values, there are no associations beyond what would be expected after controlling for the number of SNPs in each gene. The gene-based test not only controls for the number of SNPs, but also combines evidence from multiple SNPs after controlling for the linkage disequilibrium between them More...

Negative relationships between EGR3 and other components at different levels (count: 0) Help
EGR3 related SNPs in MK4MDD (count: 0)
EGR3 related proteins in MK4MDD (count: 0)
EGR3 related GO terms (count: 18)
EGR3 related KEGG pathways (count: 0)
EGR3 related BioCarta pathways (count: 1)
EGR3 related Reactome pathways (count: 0)
EGR3 related interactors from protein-protein interaction data in HPRD (count: 0)