Gene Report

Basic Information

Approved Symbol	DAOA
Approved Name	D-amino acid oxidase activator
Symbol Alias	G72
Name Alias	G72 transcript
Location	13q33.2
Position	chr13:106118216-106143383 (+)
External Links	Entrez Gene: 267012 Ensembl: ENSG00000182346 UCSC: uc010tjg.2 HGNC ID: 21191
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between DAOA and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
G72	Rietschel, 2008	patients and normal controls	chi(2) = 9.471, P-value = 0.002, OR = 9.208, 95% CI 2.129-38.899, Bonferroni-corrected P-value = 0.012	The previously identified M23-M24 risk haplotype was signifi...... The previously identified M23-M24 risk haplotype was significantly associated with major depression and high levels of neuroticism. More...

Positive relationships between DAOA and other components at different levels (count: 0)

Positive relationship network of DAOA in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between DAOA and MDD (count: 0)

Negative relationships between DAOA and other components at different levels (count: 0)

DAOA related SNPs in MK4MDD (count: 0)

DAOA related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
D-amino acid oxidase activator	P59103	0(0/0)	Gene mapped

DAOA related GO terms (count: 7)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:1900758	negative regulation of D-amino-acid oxidase activity	biological process	IDA
GO:0005739	mitochondrion	cellular component	IDA
GO:0008047	enzyme activator activity	molecular function	IDA[12364586]
GO:0005794	Golgi apparatus	cellular component	IDA[12364586]
GO:0043085	positive regulation of catalytic activity	biological process	IDA[12364586]
GO:0048471	perinuclear region of cytoplasm	cellular component	IDA
GO:0019899	enzyme binding	molecular function	IPI

DAOA related KEGG pathways (count: 0)

DAOA related BioCarta pathways (count: 0)

DAOA related Reactome pathways (count: 0)

DAOA related interactors from protein-protein interaction data in HPRD (count: 1)

Gene Report

Gene mapped GO terms