MK4MDD

Molecule Report

Basic Information
Name Cyclic AMP
Description An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.
MeSH ID D000242
No. of Studies (Positive/Negative) 1(1/0) Help

Positive relationship between Cyclic AMP and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
cAMP Mizrahi, 2004 patients and normal controls The basal concentration of cAMP was 50% lower in mononuclear...... The basal concentration of cAMP was 50% lower in mononuclear cells and lymphocytes from the depressed patients compared with the control subjects. The response to forskolin was significantly smaller in lymphocytes of major depression patients than in the controls, but no difference was evident in the mononuclear cell preparations. There was a significant increase in cAMP produced by 5HT in mononuclear cells from the control group, but not in their lymphocytes. More...

Positive relationships between Cyclic AMP and other components at different levels (count: 0) Help
Positive relationship network of Cyclic AMP in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationship between Cyclic AMP and MDD (count: 0)
Negative relationships between Cyclic AMP and other components at different levels (count: 0) Help