MK4MDD

Brain Morphology and Function Report

Basic Information
Name Corpus callosum
Brain Morphology "The corpus callosum (Latin: tough body), also known as the colossal commissure, is a wide, flat bundle of neural fibers beneath the cortex in the eutherian brain at the longitudinal fissure. It connects the left and right cerebral hemispheres and facilitates interhemispheric communication. It is the largest white matter structure in the brain, consisting of 200-250 million contralateral axonal projections."
No. of Studies (Positive/Negative) 5(5/0) Help

Positive relationships between Corpus callosum and MDD (count: 5)
Name in Literature Reference Research Type Statistical Result Relation Description Help
corpus callosum Kumar, 2004 patients and normal controls Patients had significantly lower MTRs(Magnetization transfer...... Patients had significantly lower MTRs(Magnetization transfer ratios) in the genu and splenium of the corpus callosum, the right caudate nucleus and putamen, and the occipital white matter compared with controls. More...
corpus callosum (CC) Lacerda, 2005 patients and normal controls Our findings suggest that anatomical abnormalities in CC may...... Our findings suggest that anatomical abnormalities in CC may be restricted to patients with familial MDD, with possible enlargement of CC in this particular sub-group. Patients with familial MDD had a significantly larger middle genu area (F(1,45)=4.252; p=0.045) compared to healthy controls, and significantly larger middle genu (F(1,13)=5.366; p=0.037), anterior splenium (F(1,13)=6.27; p=0.026), and middle splenium areas (F(1,13)=4.706; p=0.049) compared to patients with non-familial MDD. More...
corpus callosum Kieseppa, 2010 patients and normal controls Compared with controls, the MDD patients showed a trend for ...... Compared with controls, the MDD patients showed a trend for lower values of fractional anisotropy (FA) in the left sagittal stratum, and suggestive decreased FA in the right cingulate cortex and posterior body of corpus callosum. More...
corpus callosum Korgaonkar, 2010 patients and normal controls average reduction of 7.8% Compared with controls, melancholic participants showed an a...... Compared with controls, melancholic participants showed an average reduction of 7.8% in fractional anisotropy over WM regions associated with the limbic system, dorsolateral prefrontal cortex, thalamic projection fibers, corpus callosum, and other association fibers. More...
corpus callosum Frodl, 2012 high-risk people and normal controls The unaffected first-degree healthy relatives (UHRs) showed ...... The unaffected first-degree healthy relatives (UHRs) showed greater fractional anisotropy than controls in the body and splenium of the corpus callosum, More...

Positive relationships between Corpus callosum and other components at different levels (count: 0) Help
Positive relationship network of Corpus callosum in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Corpus callosum and MDD (count: 0)
Negative relationships between Corpus callosum and other components at different levels (count: 0) Help