MK4MDD

Brain Morphology and Function Report

Basic Information
Name Cingulate gyrus
Brain Morphology "The cingulate gyrus is an arched convolution that lies next to the corpus callosum and is separated from it by the sulcus of the corpus callosum. It begins below the rostrum, curves around in front of the genu, extends along the trunk, and then turns downward behind the splenium of the corpus callosum, where it is connected by the narrow ""isthmus of the cingulate gyrus"" to the parahippocampal gyrus. It is separated from the ""medial frontal gyrus"" by the cingulate sulcus and from the ""precuneus"" by the more variable ""suprasplenia sulcus."" It has many connections with the anterior thalamic nuclei and is often considered to be part of the ""limbic system."""
Brain Function "It is an integral part of the limbic system, which is involved with emotion formation and processing, learning, and memory, and is also important for executive function and respiratory control."
Picture Cingulate gyrus From Wiki. Magnify
No. of Studies (Positive/Negative) 7(7/0) Help

Positive relationships between Cingulate gyrus and MDD (count: 6)
Name in Literature Reference Research Type Statistical Result Relation Description Help
cingulate gyrus Smoski, 2009 patients and normal controls MDD participants showed decreased activation of the rostral ...... MDD participants showed decreased activation of the rostral cingulate gyrus during reward selection and anticipation. More...
cingulate gyrus Kano, 2004 patients and normal controls Binding (histamine H1 receptor (H(1)R) binding) potential va...... Binding (histamine H1 receptor (H(1)R) binding) potential values for [(11)C]-doxepin binding in the frontal and prefrontal cortices, and cingulate gyrus were significantly lower in the depressed patients than those in the normal control subjects. More...
cingulate gyrus Vasic, 2008 patients and normal controls Patients with depression showed reduced gray matter volume (...... Patients with depression showed reduced gray matter volume (GMV) was found in the cingulate gyrus (BA 24/32) More...
cingulate gyrus Klok, 2010 patients and normal controls P-value < .05 Significantly lower expression levels (30-50%) were detected...... Significantly lower expression levels (30-50%) were detected for MR or GR in hippocampal, inferior frontal gyrus and cingulate gyrus tissue from MDD patients (p < .05) More...
cingulate gyrus Arnold, 2011 patients and normal controls During successful encoding of positive words, patients exhib...... During successful encoding of positive words, patients exhibited a larger recruitment of a set of areas, comprising cingulate gyrus, right inferior- and left medial-frontal gyrus as well as the right anterior hippocampus/amygdala. More...
cingulate gyri Lee, 2011 patients and normal controls Decreased gray matter concentration was found in MDD patient...... Decreased gray matter concentration was found in MDD patients in the bilateral amygdalae, hippocampi, fusiform gyri, lingual gyri, insular gyri, middle-superior temporal gyri, thalami, cingulate gyri, the central lobule of the cerebellum, and the midbrain encompassing the dorsal raphe nuclei (DRN) More...

Positive relationships between Cingulate gyrus and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of Cingulate gyrus in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Cingulate gyrus and MDD (count: 0)
Negative relationships between Cingulate gyrus and other components at different levels (count: 0) Help