Gene Report

Basic Information

Approved Symbol	CHST6
Approved Name	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
Previous Symbol	MCDC1
Location	16q22
Position	chr16:75507022-75528926 (-)
External Links	Entrez Gene: 4166 Ensembl: ENSG00000183196 UCSC: uc002fef.3 HGNC ID: 6938
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between CHST6 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
CHST6	Guilloux JP, 2012	patients and normal controls		genes significantly affected in female MDD subjects genes significantly affected in female MDD subjects

Positive relationships between CHST6 and other components at different levels (count: 0)

Positive relationship network of CHST6 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between CHST6 and MDD (count: 0)

Negative relationships between CHST6 and other components at different levels (count: 0)

CHST6 related SNPs in MK4MDD (count: 0)

CHST6 related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
Carbohydrate sulfotransferase 6	Q9GZX3	0(0/0)	Gene mapped

CHST6 related GO terms (count: 11)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0030203	glycosaminoglycan metabolic process	biological process	TAS
GO:0005794	Golgi apparatus	cellular component	TAS[11181564]
GO:0018146	keratan sulfate biosynthetic process	biological process	IDA[11278593]; TAS
GO:0044281	small molecule metabolic process	biological process	TAS
GO:0005975	carbohydrate metabolic process	biological process	TAS
GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity	molecular function	IDA[11278593]; TAS[11181564]
GO:0042339	keratan sulfate metabolic process	biological process	TAS
GO:0000139	Golgi membrane	cellular component	TAS
GO:0016021	integral to membrane	cellular component	IEA
GO:0006790	sulfur compound metabolic process	biological process	IDA[11352640]
GO:0006044	N-acetylglucosamine metabolic process	biological process	IC[11181564]; IDA[11352640]

CHST6 related KEGG pathways (count: 1)

Gene mapped KEGG pathways
ID	Name	Brief Description	Full Description
hsa00533	glycosaminoglycan biosynthesis_keratan_sulfate	Glycosaminoglycan biosynthesis - keratan sulfate

CHST6 related BioCarta pathways (count: 0)

CHST6 related Reactome pathways (count: 0)

CHST6 related interactors from protein-protein interaction data in HPRD (count: 0)

Gene Report

Gene mapped GO terms

Gene mapped KEGG pathways