MK4MDD

Gene Report

Basic Information
Approved Symbol CADM1
Approved Name cell adhesion molecule 1
Previous Symbol TSLC1, IGSF4
Previous Name "tumor suppressor in lung cancer 1", "immunoglobulin superfamily, member 4"
Symbol Alias NECL2, ST17, BL2, SYNCAM, IGSF4A, Necl-2, SYNCAM1, RA175
Name Alias "nectin-like 2"
Location 11q23.2
Position chr11:115375113-115375134 (-)
External Links Entrez Gene: 23705
Ensembl: ENSG00000182985
UCSC: uc001ppi.4
HGNC ID: 5951
No. of Studies (Positive/Negative) 1(0/1) Help
Type Literature-origin

Positive relationships between CADM1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
CADM1 Redei, 2015 Patients and nomal controls P-value=0.002 Blood transcript levels of nine markers¡ªADCY3(adenylate cyc...... Blood transcript levels of nine markers¡ªADCY3(adenylate cyclase 3, which shows suggestive associationin GWASs with MDD,52 but highly significant association with body mass index in children53), DGKA, FAM46A, IGSF4A/CADM1,KIAA1539, MARCKS (myristoylated alanine-rich protein kinase C substrate, regulated by Ca2+/calmodulin), PSME1, RAPH1, and TLR7 differed significantly between MDD patients and ND controls at baseline. More...

Positive relationships between CADM1 and other components at different levels (count: 0) Help
Positive relationship network of CADM1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between CADM1 and MDD (count: 0)
Negative relationships between CADM1 and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


CADM1 related SNPs in MK4MDD (count: 0)
CADM1 related proteins in MK4MDD (count: 0)
CADM1 related GO terms (count: 35)
CADM1 related KEGG pathways (count: 1)
CADM1 related BioCarta pathways (count: 0)
CADM1 related Reactome pathways (count: 3)
CADM1 related interactors from protein-protein interaction data in HPRD (count: 6)