MK4MDD

Gene Report

Basic Information
Approved Symbol BACE1
Approved Name beta-site APP-cleaving enzyme 1
Previous Symbol BACE
Previous Name "beta-site APP-cleaving enzyme"
Location 11q23-q24
Position chr11:117186512-117186972 (-)
External Links Entrez Gene: 23621
Ensembl: ENSG00000186318
UCSC: uc001pqz.3
HGNC ID: 933
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between BACE1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
BACE1 Sequeira, 2007 patients and normal controls Selected differentially expressed genes in BA24 Selected differentially expressed genes in BA24

Positive relationships between BACE1 and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of BACE1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between BACE1 and MDD (count: 0)
Negative relationships between BACE1 and other components at different levels (count: 0) Help
BACE1 related SNPs in MK4MDD (count: 0)
BACE1 related proteins in MK4MDD (count: 0)
BACE1 related GO terms (count: 25)
BACE1 related KEGG pathways (count: 1)
BACE1 related BioCarta pathways (count: 0)
BACE1 related Reactome pathways (count: 0)
BACE1 related interactors from protein-protein interaction data in HPRD (count: 18)