Gene Report

Basic Information

Approved Symbol	B4GALT5
Approved Name	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
Symbol Alias	beta4GalT-V
Name Alias	beta4-GalT IV
Location	20q13.1-q13.2
Position	chr20:48249482-48330421 (-)
External Links	Entrez Gene: 9334 Ensembl: ENSG00000158470 UCSC: uc002xuu.4 HGNC ID: 928
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between B4GALT5 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
B4GALT5	Chu TT, 2009	Patients and nomal controls		Down regulation, fold change([MD] vs [C]) 2.5551615 Down regulation, fold change([MD] vs [C]) 2.5551615

Positive relationships between B4GALT5 and other components at different levels (count: 0)

Positive relationship network of B4GALT5 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between B4GALT5 and MDD (count: 0)

Negative relationships between B4GALT5 and other components at different levels (count: 0)

B4GALT5 related SNPs in MK4MDD (count: 0)

B4GALT5 related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
Beta-1,4-galactosyltransferase 5	O43286	0(0/0)	Gene mapped

B4GALT5 related GO terms (count: 14)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0018279	protein N-linked glycosylation via asparagine	biological process	TAS
GO:0008378	galactosyltransferase activity	molecular function	TAS[9597550]
GO:0043687	post-translational protein modification	biological process	TAS
GO:0044281	small molecule metabolic process	biological process	TAS
GO:0042339	keratan sulfate metabolic process	biological process	TAS
GO:0046872	metal ion binding	molecular function	IEA
GO:0030203	glycosaminoglycan metabolic process	biological process	TAS
GO:0018146	keratan sulfate biosynthetic process	biological process	TAS
GO:0016021	integral to membrane	cellular component	IEA
GO:0005975	carbohydrate metabolic process	biological process	TAS
GO:0000139	Golgi membrane	cellular component	TAS
GO:0032580	Golgi cisterna membrane	cellular component	IEA
GO:0016266	O-glycan processing	biological process	TAS
GO:0044267	cellular protein metabolic process	biological process	TAS

B4GALT5 related KEGG pathways (count: 1)

ID	Name	Brief Description	Full Description
Literature-origin KEGG pathway
hsa00512	o glycan_biosynthesis	O-Glycan biosynthesis	O-glycans are a class of glycans that modify serine or threo...... O-glycans are a class of glycans that modify serine or threonine residues of proteins. Biosynthesis of O-glycans starts from the transfer of N-acetylgalactosamine (GalNAc) to serine or threonine. The first GalNAc may be extended with sugars including galactose, N-acetylglucosamine, fucose, or sialic acid, but not mannose, glucose, or xylose. Depending on the sugars added, there are four common O-glycan core structures, cores 1 through 4, and an additional four, cores 5 though 8. Mucins are highly O-glycosylated glycoproteins ubiquitous in mucous secretions on cell surfaces and in body fluids. Mucin O-glycans can be branched, and many sugars or groups of sugars are antigenic. Important modifications of mucin O-glycans include O-acetylation of sialic acid and O-sulfation of galactose and N-acetylglucosamine. More...

ID	Name	Brief Description	Full Description
Gene mapped KEGG pathways

B4GALT5 related BioCarta pathways (count: 0)

B4GALT5 related Reactome pathways (count: 0)

B4GALT5 related interactors from protein-protein interaction data in HPRD (count: 0)

Gene Report

Gene mapped GO terms

Literature-origin KEGG pathway

Gene mapped KEGG pathways