MK4MDD

Pathway Report

Basic Information
Name Axon guidance
KEGG Link ID: hsa04360
Name: axon guidance
Brief Description: Axon guidance
Full Description: Axon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are read by growth cone receptors, and signal transduction pathways downstream of these receptors converge onto the Rho GTPases to elicit changes in cytoskeletal organization that determine which way the growth cone will turn.
No. of Studies (Positive/Negative) 1 (1/0) Help

Positive relationship between Axon guidance and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
Axon guidance Kao CF, 2012 patients and normal controls We found 17 significantly enriched pathways for depression We found 17 significantly enriched pathways for depression

Positive relationships between Axon guidance and other components at different levels (count: 0) Help
Positive relationship network of Axon guidance in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Axon guidance and MDD (count: 0)
Negative relationships between Axon guidance and other components at different levels (count: 0) Help
Pathway Axon guidance related genes in MK4MDD (count: 19)