MK4MDD

Gene Report

Basic Information
Approved Symbol ARHGEF7
Approved Name Rho guanine nucleotide exchange factor (GEF) 7
Symbol Alias KIAA0142, PIXB, DKFZp761K1021, Nbla10314, DKFZp686C12170, BETA-PIX, COOL1, P85SPR, P85, P85COOL1, P50BP, PAK3, P50
Name Alias "SH3 domain-containing proline-rich protein", "PAK-interacting exchange factor beta", "rho", "guanine nucleotide exchange factor 7"
Location 13q33.3
Position chr13:111955461-111958081 (+)
External Links Entrez Gene: 8874
Ensembl: ENSG00000102606
UCSC: uc001vrs.2
HGNC ID: 15607
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between ARHGEF7 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
ARHGEF7 Jansen R, 2015 patients and normal controls P-value=0.000151;FDR=0.0918;beta=-0.223 we found 129 genes (142 probesets) differentially expressed ...... we found 129 genes (142 probesets) differentially expressed between the control and current MDD groups (FDR<0.1) More...

Positive relationships between ARHGEF7 and other components at different levels (count: 0) Help
Positive relationship network of ARHGEF7 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between ARHGEF7 and MDD (count: 0)
Negative relationships between ARHGEF7 and other components at different levels (count: 0) Help
ARHGEF7 related SNPs in MK4MDD (count: 0)
ARHGEF7 related proteins in MK4MDD (count: 0)
ARHGEF7 related GO terms (count: 36)
ARHGEF7 related KEGG pathways (count: 1)
ARHGEF7 related BioCarta pathways (count: 2)
ARHGEF7 related Reactome pathways (count: 9)
ARHGEF7 related interactors from protein-protein interaction data in HPRD (count: 23)