Gene Report

Basic Information

Approved Symbol	ANLN
Approved Name	anillin, actin binding protein
Previous Name	anillin (Drosophila Scraps homolog), actin binding protein, "anillin, actin binding protein (scraps homolog, Drosophila)"
Symbol Alias	ANILLIN, Scraps, scra
Location	7p15-p14
Position	chr7:36429432-36493400 (+)
External Links	Entrez Gene: 54443 Ensembl: ENSG00000011426 UCSC: uc003tff.3 HGNC ID: 14082
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between ANLN and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
ANLN	Chu TT, 2009	Patients and nomal controls		Down regulation, fold change([MD] vs [C]) 3.8143582 Down regulation, fold change([MD] vs [C]) 3.8143582

Positive relationships between ANLN and other components at different levels (count: 0)

Positive relationship network of ANLN in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between ANLN and MDD (count: 0)

Negative relationships between ANLN and other components at different levels (count: 0)

ANLN related SNPs in MK4MDD (count: 0)

ANLN related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
Actin-binding protein anillin	Q9NQW6	0(0/0)	Gene mapped

ANLN related GO terms (count: 9)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0005826	actomyosin contractile ring	cellular component	IDA[10931866]
GO:0005634	nucleus	cellular component	IEA
GO:0003779	actin binding	molecular function	IDA[10931866]
GO:0005543	phospholipid binding	molecular function	IEA
GO:0007096	regulation of exit from mitosis	biological process	TAS[10931866]
GO:0000921	septin ring assembly	biological process	TAS[10931866]
GO:0000910	cytokinesis	biological process	IDA[10931866]
GO:0007067	mitosis	biological process	IEA
GO:0015629	actin cytoskeleton	cellular component	IDA[10931866]

ANLN related KEGG pathways (count: 0)

ANLN related BioCarta pathways (count: 0)

ANLN related Reactome pathways (count: 0)

ANLN related interactors from protein-protein interaction data in HPRD (count: 1)

Gene Report

Gene mapped GO terms