Gene Report

Basic Information

Approved Symbol	AKAP2
Approved Name	A kinase (PRKA) anchor protein 2
Previous Symbol	PRKA2
Symbol Alias	AKAP-KL, KIAA0920, DKFZp564L0716
Name Alias	protein kinase A2
Location	9q31.3
Position	chr9:112810878-112934792 (+)
External Links	Entrez Gene: 11217 Ensembl: ENSG00000241978 HGNC ID: 372
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between AKAP2 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
AKAP2	Aston, 2005	patients and normal controls		Genes altered in major depressive disorder Genes altered in major depressive disorder

Positive relationships between AKAP2 and other components at different levels (count: 0)

Positive relationship network of AKAP2 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between AKAP2 and MDD (count: 0)

Negative relationships between AKAP2 and other components at different levels (count: 0)

AKAP2 related SNPs in MK4MDD (count: 0)

AKAP2 related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
A-kinase anchor protein 2	Q9Y2D5	0(0/0)	Gene mapped

AKAP2 related GO terms (count: 1)

Gene mapped GO terms
ID	Name	Type	Evidence
GO:0019899	enzyme binding	molecular function	NAS

AKAP2 related KEGG pathways (count: 0)

AKAP2 related BioCarta pathways (count: 0)

AKAP2 related Reactome pathways (count: 0)

AKAP2 related interactors from protein-protein interaction data in HPRD (count: 1)

Gene	Interactor	Interactor in MK4MDD?	Experiment Type	PMID
AKAP2	PRKAR2A	Yes	in vitro;in vivo	12672969 , 9497389

Gene Report

Gene mapped GO terms