Gene Report

Basic Information

Approved Symbol	AIF1L
Approved Name	allograft inflammatory factor 1-like
Previous Symbol	C9orf58
Previous Name	chromosome 9 open reading frame 58
Symbol Alias	IBA2, FLJ12783
Location	9q34.13-q34.3
Position	chr9:133971863-133998539 (+)
External Links	Entrez Gene: 83543 Ensembl: ENSG00000126878 UCSC: uc004cad.2 HGNC ID: 28904
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between AIF1L and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
C9orf58	Guilloux JP, 2012	patients and normal controls		genes significantly affected in female MDD subjects genes significantly affected in female MDD subjects

Positive relationships between AIF1L and other components at different levels (count: 0)

Positive relationship network of AIF1L in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between AIF1L and MDD (count: 0)

Negative relationships between AIF1L and other components at different levels (count: 0)

AIF1L related SNPs in MK4MDD (count: 0)

AIF1L related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
Allograft inflammatory factor 1-like	Q9BQI0	0(0/0)	Gene mapped

AIF1L related GO terms (count: 7)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0005509	calcium ion binding	molecular function	IEA
GO:0032587	ruffle membrane	cellular component	IEA
GO:0015629	actin cytoskeleton	cellular component	IDA
GO:0005925	focal adhesion	cellular component	IDA
GO:0005737	cytoplasm	cellular component	IEA
GO:0005884	actin filament	cellular component	IDA[18699778]
GO:0051015	actin filament binding	molecular function	IDA[18699778]

AIF1L related KEGG pathways (count: 0)

AIF1L related BioCarta pathways (count: 0)

AIF1L related Reactome pathways (count: 0)

AIF1L related interactors from protein-protein interaction data in HPRD (count: 0)

Gene Report

Gene mapped GO terms